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Home - Products - Chromatin/Epigenetic - COX - FPL 62064

FPL 62064

CAS No. 103141-09-9

FPL 62064 ( —— )

Catalog No. M21617 CAS No. 103141-09-9

FPL 62064 is a potent ?dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetase respectively).?

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    FPL 62064
  • Note
    Research use only not for human use.
  • Brief Description
    FPL 62064 is a potent ?dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetase respectively).?
  • Description
    FPL 62064 is a potent ?dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetase respectively).?
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX;5-LOX
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    103141-09-9
  • Formula Weight
    265.31
  • Molecular Formula
    C16H15N3O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:250 mg/mL (942.29 mM; Need ultrasonic)
  • SMILES
    COc1ccc(Nc2ccn(n2)-c2ccccc2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Blackham A et al. FPL 62064 a topically active 5-lipoxygenase/cyclooxygenase inhibitor. Agents Actions. 1990 Jun;30(3-4):432-42.
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